01904nas a2200229 4500008004100000245007400041210006900115260003400184300001400218520110100232100002001333700001801353700002901371700002301400700002801423700002301451700002001474700001901494700002201513700002201535856011701557 2008 eng d00aTechniques of Virtual Dissection of the Colon Based on Spiral CT Data0 aTechniques of Virtual Dissection of the Colon Based on Spiral CT aBerlinbSpringer-Verlagc2008 a257 - 2683 a
Colorectal cancer represents the third most commonly diagnosedcancer and is the second leading cause of cancer deaths in the United States (Gazelle et al. 2000). In addition, colorectal cancer is responsible for about 11% of all new cancer cases per year (Gazelle et al. 2000). Five-year prognosis is about 90% for patients with localized disease compared to 60% if there is a regional spread and a drop to 10% in patients with distant metastasis (Gazelle et al. 2000). In the field of medicine there is a widely accepted opinion that most colorectal cancers arise from pre-existent adenomatous polyps (Johnson 2000). Therefore, different societies, such as the American Cancer Society, have proposed screening for colorectal cancer (Byers et al. 1997; Winawer et al. 1997). Today, different options exist for detection of colorectal cancer, including digital rectal examination, fecal occult blood testing, flexible and rigid sigmoidoscopy, barium enema and its variants, colonoscopy and recently computed tomography or magnetic resonance-based virtual colonography (Gazelle et al. 2000).
1 aSorantin, Erich1 aBalogh, Emese1 aBartroli, Anna, Vilanova1 aPalágyi, Kálmán1 aNyúl, László, Gábor1 aLindbichler, Franz1 aRuppert, Andrea1 aNeri, Emanuele1 aCaramella, Davide1 aBartolozzi, Carlo uhttps://www.inf.u-szeged.hu/en/publication/techniques-of-virtual-dissection-of-the-colon-based-on-spiral-ct-data00404nas a2200097 4500008004100000245009300041210006900134260004500203300001400248856004400262 2006 eng d00aNew advances for imaging laryngo / trachealstenosis by post processing of spiral-CT data0 aNew advances for imaging laryngo trachealstenosis by post proces aWien; New YorkbSpringer-Verlagc2006/// a297 - 308 uhttps://www.inf.u-szeged.hu/en/node/90903068nas a2200109 4500008004100000245012500041210006900166260004100235300001200276520262600288856004402914 2005 eng d00aTechniques in 3D Assessment of Tracheal-Stenosis by the Mean of Spiral Computed Tomography (S-CT) and Their Applications0 aTechniques in 3D Assessment of TrachealStenosis by the Mean of S aSingaporebWorld Scientificc2005/// a61 - 803 aEndotracheal intubation is the most common cause of Laryngo-Tracheal Stenoses (LTS), followed by trauma and prior airway surgery.1–3 In rare cases LTS may have resulted also from inhalation injuries, gastro-esophageal reflux disease, neoplasia and autoimmune diseases like Wegeners granulomatosis or relapsing polychondritis.1,4 In pediatric patients vascular compression of the trachea is a common cause of tracheal indentations.5 Clinical management of these conditions requires information on localization, grade, length and dynamics of the stenosis. Exact LTS information is necessary, since stenoses with a length less than 1.0 cm can be treated by an endoscopic surgery.6,7 Besides Fiberoptic Endoscopy (FE), which represents the gold standard for airway evaluation, imaging modalities like conventional radiography, fluoroscopy, tracheal tomograms, Magnetic Resonance Imaging (MRI) and above all Spiral Computed Tomography (S-CT) are an essential part of the clinical work.1,8 S-CT and the recent introduction of multislice imaging allows volumetric data acquisition of the Laryngo–Tracheal Tract (LTT) during a short time span. Decreased motion artifacts and increased spatial resolution form the basis for high quality post processing.9,10 The improved performance of today's workstations permits the use of sophisticated post processing algorithms even on standard hardware like personal computers. Thus real time 3D display and virtual endoscopic views (virtual endoscopy) are just one mouse click away. Other algorithms compute the medial axis of tubular structures like airways or vessels in 3D, which can be used for the calculation of 3D cross sectional profiles for better demonstration of caliber changes.11 Thus display of S-CT axial source images is moving rapidly to 3D display. Moreover, established network connections within and between institutions allows telemedical cooperation. Web technologies offer an easy to use way for information exchange. The objective of this paper is to present an overview on 3D display and quantification of LTS as well as to provide information how these results can be presented and shared with the referring physicians on the hospitals computer network. This article is structured in seven parts; namely: S-CT data acquisition for LTS imaging; selected 3D image post processing algorithms; 3D display; Virtual endoscopy; Objective LTS degree and length estimation using LTT 3D — cross-sectional profiles; Intranet applications; and a conclusion is drawn in the final section. uhttps://www.inf.u-szeged.hu/en/node/90801902nas a2200133 4500008004100000020001400041245012200055210006900177260001200246300001600258490000700274520144300281856004401724 2003 eng d a0033-832X00a3D cross section of the laryngotracheal tract. A new method for visualization and quantification of tracheal stenoses0 a3D cross section of the laryngotracheal tract A new method for v c2003/// a1056 - 10680 v433 aPURPOSE: Demonstration of a technique for 3D assessment oftracheal stenoses, regarding site, length and degree, based on spiral computed tomography (S-CT). PATIENTS AND METHODS: S-CT scanning and automated segmentation of the laryngo-tracheal tract (LTT) was followed by the extraction of the LTT medial axis using a skeletonisation algorithm. Orthogonal to the medial axis the LTT 3D cross sectional profile was computed and presented as line charts, where degree and length were obtained. Values for both parameters were compared between 36 patients and 18 normal controls separately. Accuracy and precision was derived from 17 phantom studies. RESULTS: Average degree and length of tracheal stenoses were found to be 60.5% and 4.32 cm in patients compared to minor caliber changes of 8.8% and 2.31 cm in normal controls (p <0.005). For the phantoms an excellent correlation between the true and computed 3D cross sectional profile was found (p <0.005) and an accuracy for length and degree measurements of 2.14 mm and 2.53% respectively could be determined. The corresponding figures for the precision were found to be 0.92 mm and 2.56%. CONCLUSION: LTT 3D cross sectional profiles permit objective, accurate and precise assessment of LTT caliber changes. Minor LTT caliber changes can be observed even in normals and, in case of an otherwise normal S-CT study, can be regarded as artefacts. uhttps://www.inf.u-szeged.hu/en/node/89501902nas a2200133 4500008004100000020001400041245012200055210006900177260001200246300001600258490000700274520144300281856004401724 2003 eng d a0033-832X00a3D cross section of the laryngotracheal tract. A new method for visualization and quantification of tracheal stenoses0 a3D cross section of the laryngotracheal tract A new method for v c2003/// a1056 - 10680 v433 aPURPOSE: Demonstration of a technique for 3D assessment oftracheal stenoses, regarding site, length and degree, based on spiral computed tomography (S-CT). PATIENTS AND METHODS: S-CT scanning and automated segmentation of the laryngo-tracheal tract (LTT) was followed by the extraction of the LTT medial axis using a skeletonisation algorithm. Orthogonal to the medial axis the LTT 3D cross sectional profile was computed and presented as line charts, where degree and length were obtained. Values for both parameters were compared between 36 patients and 18 normal controls separately. Accuracy and precision was derived from 17 phantom studies. RESULTS: Average degree and length of tracheal stenoses were found to be 60.5% and 4.32 cm in patients compared to minor caliber changes of 8.8% and 2.31 cm in normal controls (p <0.005). For the phantoms an excellent correlation between the true and computed 3D cross sectional profile was found (p <0.005) and an accuracy for length and degree measurements of 2.14 mm and 2.53% respectively could be determined. The corresponding figures for the precision were found to be 0.92 mm and 2.56%. CONCLUSION: LTT 3D cross sectional profiles permit objective, accurate and precise assessment of LTT caliber changes. Minor LTT caliber changes can be observed even in normals and, in case of an otherwise normal S-CT study, can be regarded as artefacts. uhttps://www.inf.u-szeged.hu/en/node/99801888nas a2200133 4500008004100000020001400041245007800055210006900133260001200202300001400214490000700228520147500235856004401710 2002 eng d a0278-006200aSpiral-CT-based assessment of tracheal stenoses using 3-D-skeletonization0 aSpiralCTbased assessment of tracheal stenoses using 3Dskeletoniz c2002/// a263 - 2730 v213 aPURPOSE: Demonstration of a technique for three-dimensional (3-D) assessment of tracheal-stenoses, regarding site, length and degree, based on spiral computed tomography (S-CT). PATIENTS AND METHODS: S-CT scanning and automated segmentation of the laryngo-tracheal tract (LTT) was followed by the extraction of the LTT medial axis using a skeletonization algorithm. Orthogonal to the medial axis the LTT 3-D cross-sectional profile was computed and presented as line charts, where degree and length was obtained. Values for both parameters were compared between 36 patients and 18 normal controls separately. Accuracy and precision was derived from 17 phantom studies. RESULTS: Average degree and length of tracheal stenoses was found to be 60.5% and 4.32 cm in patients compared with minor caliber changes of 8.8% and 2.31 cm in normal controls (p << 0.0001). For the phantoms an excellent correlation between the true and computed 3-D cross-sectional profile was found (p << 0.005) and an accuracy for length and degree measurements of 2.14 mm and 2.53% respectively could be determined. The corresponding figures for the precision were found to be 0.92 mm and 2.56%. CONCLUSION: LTT 3-D cross-sectional profiles permit objective, accurate and precise assessment of LTT caliber changes. Minor LTT caliber changes can be observed even in normals and, in case of an otherwise normal S-CT study, can be regarded as artifacts. uhttps://www.inf.u-szeged.hu/en/node/896