01402nas a2200169   4500008004100000020001400041245008700055210006900142260000900211300001600220490000700236520079900243100002801042700001801070700001701088856012701105       2002                        eng d  a0278-006200aMathematical generation of normal data for evaluating myocardial perfusion studies0 aMathematical generation of normal data for evaluating myocardial  c2002  a1358 - 13650 v213 aIn this paper, we present a new mathematical method that synthesizes normal data sets for quantification of regional myocardium perfusion. In clinical practice, regional myocardial perfusion is often measured with a gamma camera and quantified via circumferential profile analysis. Normal reference profile data is used to increase the accuracy of the clinical interpretations. Our goal is to create reference data from an existing set of archived studies. An iterative mathematical method, based on two statistical hypotheses, was used to generate the study set instead of collecting normal examinations from a healthy population. Clinical validation is based on interpretations by six independent observers. Results of evaluation with synthesized normal data and its validation are presented.1 aDudásné Nagy, Mariann1 aMáté, Eörs1 aKári, Béla  uhttps://www.inf.u-szeged.hu/publication/mathematical-generation-of-normal-data-for-evaluating-myocardial-perfusion-studies