01777nas a2200109   4500008004100000245006200041210006100103260004200164300001600206520140000222856004501622       2001                        eng d00aTask-specific comparison of 3D image registration methods0 aTaskspecific comparison of 3D image registration methods  aBellingham; WashingtonbSPIEc2001///  a1588 - 15983 aWe present a new class of approaches for rigid-body registrationand their evaluation in studying Multiple Sclerosis via multi 
protocol MRI. Two pairs of rigid-body registration algorithms 
were implemented, using cross- correlation and mutual 
information, operating on original gray-level images and on the 
intermediate images resulting from our new scale-based method. 
In the scale image, every voxel has the local scale value 
assigned to it, defined as the radius of the largest sphere 
centered at the voxel with homogeneous intensities. 3D data of 
the head were acquired from 10 MS patients using 6 MRI 
protocols. Images in some of the protocols have been acquired in 
registration. The co-registered pairs were used as ground truth. 
Accuracy and consistency of the 4 registration methods were 
measured within and between protocols for known amounts of 
misregistrations. Our analysis indicates that there is no best 
method. For medium and large misregistration, methods using 
mutual information, for small misregistration, and for the 
consistency tests, correlation methods using the original gray-
level images give the best results. We have previously 
demonstrated the use of local scale information in fuzzy 
connectedness segmentation and image filtering. Scale may also 
have considerable potential for image registration as suggested 
by this work.
  uhttps://www.inf.u-szeged.hu/en/node/1015